Research interests:
biology and evolution of telomeres
metabolism of phenolic compounds in yeasts
molecular biology and genetics of non-conventional yeast species
nanopore sequencing
organelle biogenesis and inheritance
structure of mitochondrial nucleoids
yeast genomics
Recent publications (2020-2023):
•Brejová, B., Hodorová, V., Lichancová, H., Peričková, E., Šoucová, V.A., Sipiczki, M., Vinař, T., & Nosek, J. (2023) Chromosome-level genome assembly of the yeast Candida verbasci. Microbiology Resource Announcements 12(3): e00005-23.
•Brejová, B., Vozáriková, V., Agarský, I., Derková, H., Fedor, M., Harmanová, D., Kiss, L., Korman, A., Pašen, M., Brázdovič, F., Vinař, T., Nosek, J., & Tomáška, Ľ. (2023) Yeast mitochondrial post-translational modification database. Genetics 224(3): iyad087.
•Červenák, F., Sepšiová, R., Peška, V., Nosek, J., & Tomáška, Ľ. (2023) Primary scientific literature represents an essential source of telomeric repeat sequences. Microbiology Spectrum 13:e0123023.
•Mixão, V., del Olmo, V., Hegedűsová, E., Saus, E., Pryszcz, L.P., Cillingová, A., Nosek, J. & Gabaldón, T. (2022) Genome analysis of five recently described species of the CUG-Ser clade uncovers Candida theae as a new hybrid lineage with pathogenic potential in the Candida parapsilosis species complex. DNA Research 29(2): dsac010.
•Cillingová, A., Tóth, R., Mojáková, A., Zeman, I., Vrzoňová, R., Siváková, B., Baráth, P., Neboháčová, M., Klepcová, Z., Brázdovič, F., Lichancová, H., Hodorová, V., Brejová, B., Vinař, T., Mutalová, S., Vozáriková, V., Mutti, G., Tomáška, Ľ., Gácser, A., Gabaldón, T. & Nosek, J. (2022) Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources. PLoS Genetics 18(3): e1009815.
•Kovacech, B., Fialova, L., Filipcik, P., Skrabana, R., Zilkova, M., Paulenka-Ivanovova, N., Kovac, A., Palova, D., Rolkova, G. P., Tomkova, K., Csokova, N. T., Markova, K., Skrabanova, M., Sinska, K., Basheer, N., Majerova, P., Hanes, J., Parrak, V., Prcina, M., Cehlar, O., Cente, M., Piestansky, J., Fresser, M., Novak, M., Slavikova, M., Borsova, K., Cabanova, V., Brejova, B., Vinař, T., Nosek, J., Klempa, B., Eyer, L., Hönig, V., Palus, M., Ruzek, D., Vyhlidalova, T., Strakova, P., Mrazkova, B., Zudova, D., Koubkova, G., Novosadova, V., Prochazka, J., Sedlacek, R., Zilka, N. & Kontsekova, E. (2022) Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern. EBioMedicine 76: 103818.
•Brejová, B., Boršová, K., Hodorová, V., Čabanová, V., Gafurov, A., Fričová, D., Neboháčová, M., Vinař, T., Klempa, B. & Nosek, J. (2021) Nanopore Sequencing of SARS-CoV-2: Comparison of Short and Long PCR-tiling Amplicon Protocols. PLoS One 16(10): e0259277.
•Boršová, K., Paul, E.D., Kováčová, V., Radvanszka, M., Hajdu, R., Čabanová, V., Sláviková, M., Ličková, M., Lukáčiková, Ľ., Belák, A., Roussier, L., Kostičová, M., Líšková, A., Maďarová, L., Štefkovičová, M., Reizigová, L., Nováková, E., Sabaka, P., Koščálová, A., Brejová, B., Vinař, T., Nosek, J., Čekan, P. & Klempa, B. (2021) Surveillance of SARS-CoV-2 lineage B.1.1.7 in Slovakia using a novel, multiplexed RT-qPCR assay: a diagnostic accuracy and surveillance study. Scientific Reports 11: 20494.
•Brejová, B., Boršová, K., Hodorová, V., Čabanová, V., Reizigová, L., Paul, E.D., Čekan, P., Klempa, B., Nosek, J. & Vinař, T. (2021) A SARS-CoV-2 mutant from B.1.258 lineage with ∆H69/∆V70 deletion in the Spike protein circulating in Central Europe in the fall 2020. Virus Genes 57(6):556-560.
•Frankovský, J., Keresztesová, B., Bellová, J., Kunová, N., Čanigová, N., Hanáková, K., Bauer, J.A., Ondrovičová, G., Lukáčová, V., Siváková, B., Zdrahal, Z., Pevala, V., Procházková, K., Nosek, J., Baráth, P., Kutejová, E. & Tomáška, Ľ. (2021) The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry 297: 101155.
•Mixão, V., Hegedűsová, E., Saus, E., Pryszcz, L.P., Cillingová, A., Nosek, J. & Gabaldón, T. (2021) Genome analysis of Candida subhashii reveals its hybrid nature and dual mitochondrial genome conformation. DNA Research 28(3): dsab006.
•Schikora-Tamarit, M.A., Marcet-Houben, M., Nosek, J. & Gabaldón, T. (2021) Shared evolutionary footprints suggest mitochondrial oxidative damage underlies multiple Complex I losses. Open Biology 11: 200362.
•Monakhova, N., Korduláková, J., Vocat, A., Egorova, A., Lepioshkin, A., Salina, E., Nosek, J., Repková, E., Zemanová, J., Jurdáková, H., Górová, R., Roh, J., Degiacomi, G., Sammartino, J.C., Pasca, M.R., Cole, S., Mikušová, K. & Makarov, V. (2021) Novel pyrano[3,2-b]indolones: design, synthesis and antimycobacterial activity. ACS Infectious Diseases 7(1): 88-100.
•Vrzoňová, R., Toth, R., Siváková, B., Moťovská, A., Gaplovská-Kyselá, K., Baráth, P., Tomáška, Ľ., Gácser, A., Gabaldón, T., Nosek, J. & Neboháčová, M. (2021) OCT1 - a yeast mitochondrial thiolase involved in the 3-oxoadipate pathway. FEMS Yeast Research 21(5): foab03
•Frankovský, J., Vozáriková, V., Nosek, J. & Tomáška, Ľ. (2021) Mitochondrial protein phosphorylation in yeast revisited. Mitochondrion 57: 148-162.
•Červenák, F. Sepšiová, R., Nosek, J. & Tomáška, Ľ. (2021). Step by step evolution of yeasst telomeres. Genome Biology & Evolution 13(2):evaa268
•Vozáriková, V., Kunová, N., Bauer, J.A., Frankovský, J., Kotrasová, V., Procházková, K., Džugasová, V., Kutejová, E., Pevala, V., Nosek, J. & Tomáška, Ľ. (2020) Mitochondrial HMG-box containing proteins: From biochemical properties to the roles in human diseases. Biomolecules 10:1193.
•Juríková, K., Gajarský, M., Hajikazemi, M., Nosek, J., Procházková, K., Paeschke, K., Trantírek, L. & Tomáška, Ľ. (2020) Role of folding kinetics of secondary structures in telomeric G-overhangs in the regulation of telomere maintenance in Saccharomyces cerevisiae. Journal of Biological Chemistry 295(27): 8958–8971.
•Tomáška, Ľ. & Nosek, J. (2020) Co-evolution in the Jungle: From Leafcutter Ant Colonies to Chromosomal Ends. Journal of Molecular Evolution 88: 293-318.
Prof. Jozef Nosek is at the Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Slovakia.
Contact:
Comenius University in Bratislava
Faculty of Natural Sciences
Department of Biochemistry
Mlynska dolina CH-1, Ilkovicova 6
842 15 Bratislava 4
Slovak Republic
Phone: +421-2-90149-402
E-mail: jozef.nosek@uniba.sk
Last update: February 08, 2024